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二维瞬时弹性成像的剪切模量成像

Shear modulus imaging with 2-D transient elastography.

作者信息

Sandrin Laurent, Tanter Mickaël, Catheline Stefan, Fink Mathias

机构信息

Laboratoire Ondes et Acoustique, Ecole Supérieure de Physique et Chimie Industrielles de la Ville de Paris, Université Denis Diderot, CNRS UMR 7587, France.

出版信息

IEEE Trans Ultrason Ferroelectr Freq Control. 2002 Apr;49(4):426-35. doi: 10.1109/58.996560.

Abstract

In previous works, we have shown that time-resolved 2-D transient elastography is a promising technique for characterizing the elasticity of soft tissues. It involves the measurement of the displacements induced by the propagation of low frequency (LF) pulsed shear waves in biological tissues. In this paper, we present a novel apparatus that contains a LF vibrating device surrounding a linear array of 128 ultrasonic transducers that performs ultrafast ultrasonic imaging (up to 10,000 frames/s) and that is able to follow in real time the propagation of a LF shear wave in the human body. The vibrating device is made of two rods, fixed to electromagnetic vibrators, that produce in the ultrasonic image area a large amplitude shear wave. The geometry has been chosen both to enhance the sensitivity and to create a quasi linear shear wave front in the imaging plane. An inversion algorithm is used to recover the shear modulus map from the spatio-temporal data, and the first experimental results obtained from tissue-equivalent materials are presented.

摘要

在之前的研究中,我们已经表明,时间分辨二维瞬态弹性成像技术是一种用于表征软组织弹性的很有前景的技术。它涉及测量低频(LF)脉冲剪切波在生物组织中传播所引起的位移。在本文中,我们展示了一种新型装置,该装置包含一个围绕128个超声换能器线性阵列的低频振动装置,该装置可进行超快速超声成像(高达10000帧/秒),并且能够实时跟踪低频剪切波在人体中的传播。振动装置由两根固定在电磁振动器上的杆组成,它们在超声图像区域产生大幅度剪切波。选择这种几何结构既是为了提高灵敏度,也是为了在成像平面中创建一个准线性剪切波前。使用反演算法从时空数据中恢复剪切模量图,并展示了从组织等效材料获得的首批实验结果。

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