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与腹膜透析相关的耐万古霉素腹膜炎:一个值得关注的问题。

Vancomycin-resistant peritonitis associated with peritoneal dialysis: a cause for concern.

作者信息

O'Riordan A, Abraham K A, Ho J Kee, Walshe J J

机构信息

Department of Nephrology and Transplantation, Beaumont Hospital, Dublin, Ireland.

出版信息

Ir J Med Sci. 2002 Jan-Mar;171(1):42-3. doi: 10.1007/BF03168942.

Abstract

BACKGROUND

Peritonitis resulting from peritoneal dialysis (PD) remains a serious cause of morbidity and even mortality among dialysis patients.

AIM

To highlight the danger of antibiotic resistance in patients on dialysis who have received multiple courses of antibiotics.

METHODS

Two cases are reported in which the patients developed peritonitis resistant to vancomycin.

CONCLUSIONS

Multi-drug resistance is a growing danger. It is imperative to use the most appropriate antibiotics in the proper dosage. If infections persist, early removal of the catheters is essential. The use of antibiotics in PD patients needs to be limited. Sensitivity patterns of the cultured organisms must be monitored regularly as the lack of vigilance may help accelerate the development of the so-called 'super bug' resistant to all antibiotics.

摘要

背景

腹膜透析(PD)所致腹膜炎仍是透析患者发病甚至死亡的严重原因。

目的

强调接受多疗程抗生素治疗的透析患者发生抗生素耐药的危险性。

方法

报告两例患者发生对万古霉素耐药的腹膜炎。

结论

多重耐药是日益严重的危险。必须使用适当剂量的最合适抗生素。如果感染持续存在,尽早拔除导管至关重要。腹膜透析患者抗生素的使用需要加以限制。必须定期监测培养出的微生物的敏感性模式,因为缺乏警惕可能会加速对所有抗生素均耐药的所谓“超级细菌”的出现。

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