Antonescu C R, Huvos A G
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Am J Clin Pathol. 2000 Nov;114 Suppl:S90-103. doi: 10.1093/ppr/114.1.s90.
Osteosarcomas represent a heterogeneous group of tumors with different histologic and clinical features, biologic behavior, and therapy. Histologic grading has remained the most important factor for predicting the clinical progression of osteosarcomas. Some of the most common diagnostic problems in surgical pathology related to low-grade osteogenic sarcoma are addressed.
骨肉瘤是一组具有不同组织学和临床特征、生物学行为及治疗方法的异质性肿瘤。组织学分级一直是预测骨肉瘤临床进展的最重要因素。本文探讨了外科病理学中与低级别骨肉瘤相关的一些最常见诊断问题。