与畸形红细胞相比，棘形红细胞尿在区分肾小球性血尿和非肾小球性血尿方面更有效。 （注：原英文句子存在语法错误，正确表述应该是“Acanthocyturia is more efficient in differentiating glomerular from non-glomerular hematuria than dysmorphic erythrocytes.” ）
[Acanthocyturia is more efficient in to differentiate glomerular from non-glomerular hematuria then dysmorphic erythrocytes].
作者信息
Catalá López José Luis, Fábregas Brouard Marian
机构信息
Servicio de Bioquímica Clínica, Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria, España.
出版信息
Arch Esp Urol. 2002 Mar;55(2):164-6.
OBJECTIVE
Our purpose was to determine which was the most reliable method for differentiating glomerular from non-glomerular (lower urinary tract) hematuria by microscopic examination of urinary red blood cells: dysmorphic red cell count or acanthocyte count. The latter is a special type of dysmorphic red cell specific to glomerular hematuria.
METHODS
Urine samples of 170 patients with hematuria [73 had renal and 97 non-renal (urological) pathology] were analyzed. Urinary sediment phase-contrast microscopy was performed to determine the percentage of dysmorphic red cells and acanthocytes in each patient. Data were correlated with the diagnosis.
RESULTS
Glomerular hematuria defined as dysmorphic red cell count > 35% showed a sensitivity and specificity of 69% and 100%, respectively. Glomerular hematuria defined as acanthocytes > 5% showed a sensitivity and specificity of 88% and 100%, respectively.
CONCLUSIONS
Phase-contrast microscopy urinary sediment acanthocyte count is more effective than dysmorphic red cell count in the diagnosis of glomerular hematuria.
目的
我们的目的是通过对尿红细胞进行显微镜检查，确定区分肾小球性血尿与非肾小球性（下尿路）血尿最可靠的方法：异形红细胞计数还是棘形红细胞计数。后者是肾小球性血尿特有的一种特殊类型的异形红细胞。
方法
分析了170例血尿患者的尿液样本[73例有肾脏病变，97例有非肾脏（泌尿外科）病变]。进行尿沉渣相差显微镜检查以确定每位患者异形红细胞和棘形红细胞的百分比。数据与诊断结果相关联。
结果
定义为异形红细胞计数>35%的肾小球性血尿，其敏感性和特异性分别为69%和100%。定义为棘形红细胞>5%的肾小球性血尿，其敏感性和特异性分别为88%和100%。
结论
在诊断肾小球性血尿方面，尿沉渣棘形红细胞计数比异形红细胞计数更有效。
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