Dermietzel R
Cell Tissue Res. 1975 Dec 10;164(3):309-29. doi: 10.1007/BF00223012.
The leptomeningeal tissue of the choroid plexuses and of the brain surfaces have been studied by means of the freeze-etching technique. The pia-arachnoid membrane and the subdural neurothel represent the morphological barrier between the extracerebral tissue and the cerebrospinal compartment. The freeze-etch findings indicate that the arachnoid and neurothelial cells are coupled by extensive zonulae occludentes which seem to represent the structural basis of the barrier mechanism provided by these cell layers. Furthermore, it became evident that gap junctions of considerable structural heterogeneity occur on the pial and arachnoid cells of the interstitial choroidal compartment and of the free brain surfaces. The structural heterogeneity of the nexuses is taken as an indication of the plasticity of the leptomeningeal tissue. The different morphological characteristics of the nexal formations are discussed with respect to their probable functional meaning.
已通过冷冻蚀刻技术对脉络丛和脑表面的软脑膜组织进行了研究。软脑膜-蛛网膜和硬膜下神经上皮代表了脑外组织与脑脊液腔之间的形态学屏障。冷冻蚀刻结果表明，蛛网膜细胞和神经上皮细胞通过广泛的紧密连接相连，这些紧密连接似乎代表了这些细胞层所提供屏障机制的结构基础。此外，很明显，在脉络膜间隙和游离脑表面的软膜和蛛网膜细胞上存在结构异质性相当大的缝隙连接。连接结构的异质性被视为软脑膜组织可塑性的一个指标。针对连接结构可能的功能意义，讨论了连接结构的不同形态特征。
