Seah L L, Choo C T, Fong K S
Oculoplastic Service, Singapore National Eye Centre, Singapore.
Ophthalmic Plast Reconstr Surg. 2002 May;18(3):190-5. doi: 10.1097/00002341-200205000-00007.
Congenital upper lid colobomas may be associated with ocular and systemic anomalies. The ophthalmologist's role involves both the diagnosis and management of their various ocular structural defects and management of the visual development.
All cases of congenital eyelid colobomas referred to the Singapore National Eye Centre between July 1992 and July 1995 were assessed for the extent of the eyelid defect, associated ocular anomalies, status of the cornea, and any systemic anomalies.
Four infants were tested during this period. The mean follow-up was 25 months (range, 16 to 30 months). All required surgical correction of their eyelid defects before 2 years of age. The patients also had refractive errors requiring amblyopia management. Three of the babies also needed other surgical procedures.
Congenital upper eyelid colobomas are a potential threat to vision at an early age and a significant cosmetic blemish later in life. Early surgical intervention is usually required when the defect is larger than one third of the eyelid margin. Close monitoring of the visual development of patients with congenital upper eyelid colobomas is also essential since the risk of amblyopia in these patients is high.
先天性上睑缺损可能与眼部及全身异常有关。眼科医生的职责包括诊断和处理各种眼部结构缺陷以及管理视觉发育。
对1992年7月至1995年7月间转诊至新加坡国立眼科中心的所有先天性眼睑缺损病例进行评估，内容包括眼睑缺损的程度、相关眼部异常、角膜状况以及任何全身异常。
在此期间对4名婴儿进行了检查。平均随访时间为25个月（范围16至30个月）。所有患儿均需在2岁前接受眼睑缺损的手术矫正。这些患者还存在屈光不正，需要进行弱视治疗。其中3名婴儿还需要其他外科手术。
先天性上睑缺损在早期对视力构成潜在威胁，在后期会造成明显的美容缺陷。当缺损大于眼睑边缘的三分之一时，通常需要早期手术干预。密切监测先天性上睑缺损患者的视觉发育也至关重要，因为这些患者弱视风险很高。
