甲硫威对鹩哥、鸽子和鹌鹑的慢性毒性以及对鹌鹑的生殖影响。

The chronic toxicity of methiocarb to grackles, doves, and quail and reproductive effect in quail.

作者信息

Schafer E W, Brunton R B, Lockyer N F, Cunningham D J

出版信息

Bull Environ Contam Toxicol. 1975 Dec;14(6):641-7. doi: 10.1007/BF01685236.

PMID:1203576

Abstract

Methiocarb (4-methylthio-3, 5-xylyl N-methyl carbamate, Mesurol, Bay (3744), a bird repellent, was fed in concentrations of 100 to 1,000 ppm to common grackles (Quiscalus quiscula), mourning doves (Zenaida macroura), and breeding pairs of coturnix quail (Coturnix coturnix) to investigate the possibility of cumulative intoxication. Although aversion to treated diets was readily apparent in most of the tests, the 28- to 30-day median lethal concentration (LC50) was determined to be greater than 100 ppm for grackles, 630 ppm (95% confidence limits, 480-830 ppm) for doves, and greater than 1,000 ppm for coturnix quail. Methiocarb appeared to be noncumulative when measured by an index of chronicity: birds consumed several LD50 doses during a day's feeding, and when deaths occurred, they appeared to be due to acute intoxication. Egg production and live chick production were not affected in coturnix fed 100 ppm but were reduced at 316 and 1,000 ppm.

摘要

灭虫威（4-甲硫基-3,5-二甲苯基N-甲基氨基甲酸酯，灭梭威，拜耳（3744），一种驱鸟剂），以100至1000 ppm的浓度投喂给普通拟椋鸟（Quiscalus quiscula）、哀鸽（Zenaida macroura）和鹌鹑繁殖对（Coturnix coturnix），以研究累积中毒的可能性。尽管在大多数试验中对经处理的饲料的厌恶很明显，但对于拟椋鸟，28至30天的半数致死浓度（LC50）测定为大于100 ppm，对于鸽子为630 ppm（95%置信限，480 - 830 ppm），对于鹌鹑大于1000 ppm。当通过慢性指数测量时，灭虫威似乎没有累积性：鸟类在一天的喂食中摄入了几个半数致死剂量，并且当死亡发生时，似乎是由于急性中毒。喂食100 ppm灭虫威的鹌鹑的产蛋量和活雏鸡产量没有受到影响，但在316 ppm和1000 ppm时有所下降。