Uy Harvey S, de Jesus Arnel A, Paray Alvin A, Flores John D G, Felizar Loreto B
University of the Philippines, Philippine General Hospital, Ermita, Manila, Philippines.
J Cataract Refract Surg. 2002 Jun;28(6):1023-6. doi: 10.1016/s0886-3350(02)01268-3.
To compare the efficacy of ropivacaine mixed with lidocaine and bupivacaine mixed with lidocaine for retrobulbar anesthesia in cataract surgery.
Philippine General Hospital, Manila, Philippines.
This prospective double-masked study consisted of 80 patients randomized to receive ropivacaine 1%-lidocaine 2% (Group 1) or bupivacaine 0.5%-lidocaine 2% (Group 2) for retrobulbar anesthesia during extracapsular cataract extraction (ECCE). The main outcome measures were frequency of eye pain and amount of globe movement. The degree of pain was scored from 0 to 10 using a visual analog scale. Globe movement in 4 directions of gaze was measured with a ruler.
The number of patients with visual analog system scores greater than zero at 5 minutes after infiltration, 10 minutes after infiltration, intraoperatively, and 1, 2, and 4 hours postoperatively was 0, 0, 0, 1, 18, and 29, respectively, in Group 1 and 1, 1, 0, 1, 21, and 33, respectively, in Group 2. The mean globe movement at 5 minutes, 10 minutes after infiltration, and intraoperatively was 5.1 mm, 3.0 mm, and 0.6 mm, respectively, in Group 1 and 4.9 mm, 3.0 mm, and 0.3 mm, respectively, in Group 2. There were no significant differences in frequency of pain and amount of globe movement between the 2 groups at any time. No adverse reactions developed in either group. The duration of surgery was similar between groups.
Ropivacaine mixed with lidocaine and bupivacaine mixed with lidocaine were equally effective in producing ocular analgesia and akinesia for ECCE.
比较罗哌卡因与利多卡因混合液和布比卡因与利多卡因混合液在白内障手术球后麻醉中的效果。
菲律宾马尼拉市菲律宾总医院。
这项前瞻性双盲研究纳入80例患者,随机分为两组,分别在白内障囊外摘除术(ECCE)期间接受1%罗哌卡因-2%利多卡因(第1组)或0.5%布比卡因-2%利多卡因(第2组)进行球后麻醉。主要观察指标为眼痛频率和眼球活动度。疼痛程度采用视觉模拟评分法从0至10分进行评分。用直尺测量注视4个方向时的眼球活动度。
第1组在浸润后5分钟、浸润后10分钟、术中、术后1小时、2小时和4小时视觉模拟系统评分大于零的患者数分别为0、0、0、1、18和29例,第2组分别为1、1、0、1、21和33例。第1组浸润后5分钟、10分钟和术中的平均眼球活动度分别为5.1毫米、3.0毫米和0.6毫米,第2组分别为4.9毫米、3.0毫米和0.3毫米。两组在任何时间的疼痛频率和眼球活动度均无显著差异。两组均未出现不良反应。两组手术时间相似。
罗哌卡因与利多卡因混合液和布比卡因与利多卡因混合液在为ECCE产生眼部镇痛和运动不能方面同样有效。