Chang Ming-Hong, Wei S-J, Chiang H-L, Wang H-M, Hsieh P F, Huang S-Y
Section of Neurology, Taichung Veterans General Hospital, No. 160 Chung-Kang Road, Section 3, Taichung, Taiwan 40705.
Neurology. 2002 Jun 11;58(11):1603-7. doi: 10.1212/wnl.58.11.1603.
To compare the sensitivities of motor wrist-to-palm (W-P) conduction velocity and two median-ulnar motor latency differences with that of sensory W-P conduction velocity in the diagnosis of carpal tunnel syndrome (CTS).
This study included 116 consecutive patients with CTS (160 hands) referred for evaluation and 100 volunteers who served as controls. Median motor and sensory nerve responses with wrist and palm stimulation allowed for the determination of motor and sensory W-P CV (W-P MCV and SCV). Two motor distal latency (MDL) differences between the median-thenar and ulnar-hypothenar (M-U) muscles and between the median-second lumbrical and ulnar-interossei muscles (2L-INT) were measured and calculated. The mean values of controls plus or minus 2.5 SD served as the normal limits.
Among the 160 hands with suspected CTS, 11 (6.88%) had normal electrodiagnostic studies and 149 (93.1%) had at least one abnormal electrodiagnostic study. Among the 149 hands with an abnormality, 139 (86.88%) had abnormal W-P MCV and 129 (80.63%) had abnormal W-P SCV. The sensitivity for 2L-INT was 77.5%, and it was 70% for M-U, 68.75% for median MDL, and 73.75% for sensory distal latency. Combining W-P MCV and W-P SCV allowed for the detection of abnormalities in 147 hands (91.88%) and yielded a markedly improved diagnostic rate compared with W-P SCV alone.
Motor W-P conduction study is more valuable and no more difficult than sensory W-P conduction study for the diagnosis of CTS. In patients with suspected CTS in whom the results of conventional nerve conduction studies are normal, studying both motor and sensory W-P conduction increases the diagnostic yield.
比较运动性腕至掌(W-P)传导速度以及正中神经与尺神经运动潜伏期的两种差异与感觉性W-P传导速度在诊断腕管综合征(CTS)中的敏感性。
本研究纳入了116例连续转诊评估的CTS患者(160只手)以及100名作为对照的志愿者。通过腕部和掌部刺激获得正中神经运动和感觉神经反应,以测定运动和感觉性W-P CV(W-P MCV和SCV)。测量并计算了拇短展肌与小指展肌之间(M-U)以及第2蚓状肌与骨间肌之间(2L-INT)的两个运动远端潜伏期(MDL)差异。对照组平均值加减2.5个标准差作为正常范围。
在160只疑似CTS的手中,11只(6.88%)电诊断检查结果正常,149只(93.1%)至少有一项电诊断检查异常。在149只异常的手中,139只(86.88%)W-P MCV异常,129只(80.63%)W-P SCV异常。2L-INT的敏感性为77.5%,M-U为70%,正中神经MDL为68.75%,感觉远端潜伏期为73.75%。联合W-P MCV和W-P SCV可检测出147只手(91.88%)的异常,与单独使用W-P SCV相比,诊断率显著提高。
对于CTS的诊断,运动性W-P传导研究比感觉性W-P传导研究更有价值且难度相当。对于疑似CTS但常规神经传导研究结果正常的患者,同时研究运动和感觉性W-P传导可提高诊断率。