Aldemir Mustafa, Baç Bilsel, Taçyildiz Ibrahim, Yağmur Yusuf, Keleş Celalettin
Department of General Surgery, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Surg Today. 2002;32(5):450-3. doi: 10.1007/s005950200074.
Subcapsular liver hematomas and ruptures are unusual fatal complications of HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome (HS). We present two cases of a spontaneous rupture of subcapsular liver hematoma occurring in HS and review the literature on this subjects. One case demonstrated a secondary rupture of a subcapsulary liver hematoma due to HS in one patient and HS associated with preeclampsia in another. The defects were on the medial and lateral sectors of the left lobe in one patient and on the medial sector of the right lobe in the other patient. In case 1 deep mattress sutures and omentoplasty were performed, and in the other case a defective area was closed with an absorbable gelatin sponge with a hemostatic effect. In addition, the liver was compressed by abdominal towels. A high index of suspicion and immediate recognition are keys to proper diagnosis and management of affected patients. The multidisciplinary approach to the management of these patients led to a remarkable decrease in the mortality rates. Less aggressive treatment is preferable to aggressive intervention such as a hepatic resection in such patients with coagulopathy.
肝包膜下血肿和破裂是溶血、肝酶升高和血小板减少(HELLP)综合征(HS)罕见的致命并发症。我们报告两例HS患者发生肝包膜下血肿自发性破裂的病例,并回顾关于该主题的文献。一例显示一名患者因HS导致肝包膜下血肿继发性破裂,另一例显示HS合并先兆子痫。缺损分别位于一名患者左叶的内侧和外侧段,以及另一名患者右叶的内侧段。病例1采用了深部褥式缝合和网膜成形术,另一例则用具有止血作用的可吸收明胶海绵封闭缺损区域。此外,用腹带压迫肝脏。高度的怀疑指数和及时识别是正确诊断和处理受影响患者的关键。对这些患者采用多学科管理方法可显著降低死亡率。对于此类有凝血功能障碍的患者,采取较保守的治疗方法优于诸如肝切除术等积极干预措施。