理论上的形态发生素梯度

Morphogen gradients, in theory.

作者信息

Freeman Matthew

机构信息

MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom.

出版信息

Dev Cell. 2002 Jun;2(6):689-90. doi: 10.1016/s1534-5807(02)00193-4.

DOI:10.1016/s1534-5807(02)00193-4

PMID:12062079

Abstract

The idea that morphogen gradients are established by a process of repeated cycles of exocytosis and endocytosis-so-called planar transcytosis-has been gaining acceptance. This is now challenged by a theoretical approach that experimental biologists should not dismiss; diffusive mechanisms of gradient formation may be correct after all.

摘要

形态发生素梯度是通过胞吐作用和胞吞作用的重复循环过程（即所谓的平面转胞吞作用）建立的这一观点已逐渐被接受。现在，一种理论方法对这一观点提出了挑战，实验生物学家不应忽视这种方法；梯度形成的扩散机制可能终究是正确的。