Serment H, Erny R, Piana L, Espesset A
J Gynecol Obstet Biol Reprod (Paris). 1975 Jul-Aug;4(5):733-46.
We have been using two products, one an alpha-blocker (Vadilex) and the other a beta-stimulating drug (Ritodrine) to treat cases with threatened premature labour. Our experience is with 93 women who were treated in a continuous series. The overall result of our treatment show that 72 per cent of the cases were treated successfully and 28 failed. Analysing these preliminary figures in greater detail we have observed that the prognosis depends mainly on the state of the cervix at the time treatment is started in cases of threatened premature labour. The chances for success are much greater if the cervix is long and closed that if it is taken up or open. Since the trial was not carried out with a "double blind" control, we cannot really tell which of the two products we used was more efficacious.
我们一直在使用两种药物治疗先兆早产病例,一种是α受体阻滞剂(Vadilex),另一种是β受体激动剂(利托君)。我们连续治疗了93名女性患者。治疗的总体结果显示,72%的病例治疗成功,28例失败。对这些初步数据进行更详细的分析后,我们观察到,在先兆早产病例中,预后主要取决于开始治疗时宫颈的状态。如果宫颈长且闭合,成功的几率要比宫颈已消失或开放时大得多。由于该试验没有采用“双盲”对照,我们无法确切判断所使用的两种药物中哪一种更有效。