Carli Paule-Marie, Maynadié Marc
INSERM/IVS no. 4T003C Faculté de médecine BP 87900, 21079 Dijon.
Rev Prat. 2002 May 1;52(9):945-50.
Nowadays, non-hodgkin lymphoma (NHL) presents the fifth highest cancer incidence rate. It is one of the few cancers in which incidence has been increasing over the last decades in the world. Even though therapeutic progress allow a favourable evolution in one case out of two, NHL remains preoccupying, especially because of the lack of knowledge regarding its aetiology. Indeed, several factors have been studied and may play a concomitant role: factors linked to genetics, immunodepression, viruses, professional or non-professional toxics. We will review results from different studies evaluating the role of those factors after having reported current knowledge on NHL.
如今,非霍奇金淋巴瘤(NHL)是癌症发病率第五高的疾病。它是过去几十年来全球发病率一直在上升的少数几种癌症之一。尽管治疗取得了进展,每两个病例中就有一个能有良好的病情发展,但NHL仍然令人担忧,尤其是因为对其病因缺乏了解。事实上,已经对几个因素进行了研究,它们可能共同起作用:与遗传、免疫抑制、病毒、职业或非职业毒素相关的因素。在报告了目前关于NHL的知识后,我们将回顾不同研究评估这些因素作用的结果。