Yamada Terumasa, Sasaki Yo, Yokoyama Shigekazu, Miyashiro Isao, Murata Kohei, Doki Yuichiro, Kameyama Masao, Ohigashi Hiroaki, Hiratsuka Masahiro, Ishikawa Osamu, Imaoka Shingi
Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
Hepatogastroenterology. 2002 May-Jun;49(45):597-600.
BACKGROUND/AIMS: Because less surgical stress might preserve quality of life of patients, it is more desirable to decrease both intraoperative blood loss and liver injury especially in hepatectomy. For the patients with hepatocellular carcinoma based on chronic liver dysfunction, it is more essential to control bleeding and reduce liver injury in hepatectomy than in other diseases. In the present study, a retrospective comparison about usefulness was made in hepatectomy between using bipolar scissors and using conventional procedure. Before 1997, in our hospital, we had dissected the liver by using the crushing clamp method in combination with cauterization by microwave coagulator for the purpose of reducing intraoperative blood loss. Since 1998, bipolar scissors have been introduced toward hepatectomy as a new, simple and easy device to use.
Fifty-three consecutive patients with primary hepatocellular carcinoma at TNM stage I/II who underwent partial hepatectomy between 1996 and 1999 were enrolled in the study. Thirty-two patients (1996-1997) were treated by using a conventional method (group CM) and 21 patients (1998-1999) were treated by using bipolar scissors (group BS). The factors related to surgical stress were compared between the two groups.
The amounts of blood loss/transfusion were lower in group BS (641/100 mL) than in group CM (1112/450 mL). The percentages of patients who lost more than 1000 mL of blood were lower in group BS (19%) than in group CM (47%) (P = 0.04). An intraabdominal drainage was needed for 9.0 +/- 6.6 days in group BS, and the drainage period was shorter than that in group CM (15.0 +/- 8.7 days) (P = 0.01).
These results indicated the superiority of bipolar scissors in decreasing blood loss and liver injury to the conventional method, suggesting the worth of performing the prospective randomized study.
背景/目的:由于较低的手术应激可能有助于维持患者的生活质量,因此更希望减少术中失血和肝损伤,尤其是在肝切除术中。对于基于慢性肝功能障碍的肝细胞癌患者,在肝切除术中控制出血和减少肝损伤比其他疾病更为重要。在本研究中,对使用双极电剪和传统手术方法在肝切除术中的有效性进行了回顾性比较。1997年以前,在我们医院,为了减少术中失血,我们采用压榨钳法结合微波凝固器烧灼来解剖肝脏。自1998年以来,双极电剪作为一种新的、简单易用的设备被引入肝切除术。
选取1996年至1999年间连续接受部分肝切除术的53例TNM I/II期原发性肝细胞癌患者纳入研究。32例患者(1996 - 1997年)采用传统方法治疗(CM组),21例患者(1998 - 1999年)采用双极电剪治疗(BS组)。比较两组与手术应激相关的因素。
BS组的失血量/输血量(641/100 mL)低于CM组(1112/450 mL)。失血量超过1000 mL的患者百分比在BS组(19%)低于CM组(47%)(P = 0.04)。BS组腹腔引流需要9.0±6.6天,引流时间短于CM组(15.0±8.7天)(P = 0.01)。
这些结果表明双极电剪在减少失血和肝损伤方面优于传统方法,提示进行前瞻性随机研究的价值。