Alpha-fetoprotein- and des-gamma-carboxy prothrombin-producing advanced gastric cancer.

作者信息

Ando Eiji, Oriishi Tetsuharu, Toyonaga Atsushi, Tobaru Takeshi, Tanaka Masatoshi, Shimamura Ryuji, Terai Yuji, Nakajima Yutaka, Sata Michio

机构信息

Department of Medicine II, Kurume University School of Medicine, 67, Asahi-Machi, Kurume-shi, Fukuoka-ken, 830-0011, Japan.

出版信息

Eur J Gastroenterol Hepatol. 2002 Jun;14(6):687-91. doi: 10.1097/00042737-200206000-00015.

DOI:10.1097/00042737-200206000-00015

PMID:12072604

Abstract

A case of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) producing gastric cancer with multiple liver metastasis is reported. The simultaneous presence of Borrmann I gastric cancer and IIa aggregating type gastric cancer was noted. Borrmann I gastric cancer was a poorly differentiated adenocarcinoma, while IIa aggregating type gastric cancer was a moderately differentiated adenocarcinoma. Plasma levels of AFP and DCP were 247,000 ng/ml and 320,000 mAU/ml, respectively. Immunohistochemical staining confirmed the production of these two proteins in Borrmann I gastric cancer.

摘要