使用乙二胺四乙酸（EDTA）血样进行甘露糖苷贮积症检测。
Use of EDTA blood samples for mannosidosis testing.
作者信息
Healy P J, Butrej P J
出版信息
Aust Vet J. 1979 Nov;55(11):534-6. doi: 10.1111/j.1751-0813.1979.tb07022.x.
Abstract
Preincubation of EDTA plasma with 4mM ZnCl2 restores acidic alpha mannosidase activity, previously inhibited as a result of chelation of Zn++ by EDTA. This allows estimation of acidic alpha mannosidase activity in EDTA plasma samples, followed by granulocyte tests on those samples with low activities.
摘要
用4mM氯化锌对乙二胺四乙酸（EDTA）血浆进行预孵育，可恢复酸性α-甘露糖苷酶的活性，该活性先前因EDTA对锌离子的螯合作用而受到抑制。这使得能够对EDTA血浆样本中的酸性α-甘露糖苷酶活性进行评估，随后对那些活性较低的样本进行粒细胞检测。
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