Timurkaynak Timur, Ozdemir Murat, Cengel Atiye, Cemri Mustafa, Ciftci Haci, Yalcin Ridvan, Boyaci Bulent, Dortlemez Ovsev, Dortlemez Halis
Gazi University Medical School, Department of Cardiology, Ankara, Turkey.
J Invasive Cardiol. 2002 Jul;14(7):372-7.
There are no data regarding the potential benefits of direct stenting in the setting of AMI. The aim of this study was to evaluate the impact of direct stenting on the angiographic results and compare it to conventional stenting performed in the setting of AMI. We reviewed our institutional interventional database and identified 44 patients who had undergone stenting in the setting of AMI (29 primary and 15 rescue angioplasty). Patients were then divided into two groups; group A consisted of patients who had undergone conventional stenting (23 patients) and group B those who had undergone direct stenting (21 patients). Angiographic success was defined as TIMI flow grade 2. The baseline TIMI 0-1 flow was higher in group A compared to group B (74% vs. 24%; p < 0.05). TIMI flow rates before stenting (after balloon predilation in group A and after guidewire crossing in group B) and angiographic success (TIMI flow 2) after stenting were similar in both groups (p > 0.05). However, the final TIMI 3 flow were significantly better in group B after stenting (65% vs. 95%; p < 0.05). Although there was no no re-flow in group B, three patients in group A had no re-flow after balloon predilatation of lesions with baseline TIMI 2 flow. There was a statistical tendency to a higher TIMI 3 flow in patients treated with direct stenting in the setting of AMI. Direct stenting strategy in thrombus containing lesions seems to be a safe and feasible approach in avoiding no re-flow.
关于急性心肌梗死(AMI)情况下直接支架置入术的潜在益处尚无相关数据。本研究的目的是评估直接支架置入术对血管造影结果的影响,并将其与AMI情况下进行的传统支架置入术进行比较。我们回顾了我们机构的介入数据库,确定了44例在AMI情况下接受支架置入术的患者(29例直接PCI和15例补救性血管成形术)。然后将患者分为两组;A组由接受传统支架置入术的患者组成(23例),B组由接受直接支架置入术的患者组成(21例)。血管造影成功定义为TIMI血流分级2级。A组的基线TIMI 0 - 1级血流高于B组(74%对24%;p < 0.05)。两组在支架置入前的TIMI血流率(A组在球囊预扩张后,B组在导丝穿过病变后)和支架置入后的血管造影成功率(TIMI血流2级)相似(p > 0.05)。然而,B组在支架置入后的最终TIMI 3级血流明显更好(65%对95%;p < 0.05)。虽然B组没有出现无复流现象,但A组有3例患者在病变球囊预扩张后出现无复流,其基线TIMI血流为2级。在AMI情况下接受直接支架置入术的患者中,TIMI 3级血流有更高的统计学趋势。在含血栓病变中采用直接支架置入策略似乎是一种避免无复流的安全可行方法。