de Palma Luigi, Rapali Stefano, Paladini Paolo, Ventura Angelo
Department of Orthopedics, University of Ancona, Italy.
Orthopedics. 2002 Jun;25(6):665-8. doi: 10.3928/0147-7447-20020601-17.
Heterotopic ossification is a disorder characterized histologically and radiographically by normal bone formation in soft tissues that normally have no ossification properties. In severe head-trauma patients, a high incidence of heterotopic ossification occurs. The diagnosis of this pathology in these patients often is difficult for residual neurological damage. The etiology of heterotopic ossification following head trauma is unknown. Similarities have been found between heterotopic ossification and myositis ossificans, a hereditary autosomal dominant disease.
异位骨化是一种在组织学和影像学上表现为在正常情况下无骨化特性的软组织中形成正常骨的病症。在严重颅脑外伤患者中,异位骨化的发生率很高。由于存在残留神经损伤,这些患者中这种病症的诊断往往很困难。头部外伤后异位骨化的病因尚不清楚。异位骨化与骨化性肌炎(一种常染色体显性遗传病)之间已发现有相似之处。