Solodenko Wladimir, Kunz Ulrich, Jas Gerhard, Kirschning Andreas
Institut für Organische Chemie der Universität Hannover, Schneiderberg 1B, Germany.
Bioorg Med Chem Lett. 2002 Jul 22;12(14):1833-5. doi: 10.1016/s0960-894x(02)00265-2.
A PASSflow protocol for the Horner-Emmons olefination of aldehydes using polymer-bound hydroxide ions in flowthrough reactors is presented which allows preparation of alkenes in very high yield with minimal purification.