[肝硬化患者肝性脑病联合治疗的疗效]
[The response to combined therapy of hepatic encephalopathy in patients with hepatic cirrhosis].
作者信息
Maev I V, V'iuchnova E S, Lebedeva E G, Iakovenko E I, Dicheva D T
出版信息
Klin Med (Mosk). 2002;80(5):42-5.
PMID:12087887
Abstract
Combined therapy with gepa-merz (L-ornitine-L-aspartate) and lactulose (a synthetic disaccharide) was given to 40 patients with hepatic encephalopathy and toxic hepatic cirrhosis in decompensation. Combination of gepa-merz with lactulose was effective in the above patients. Moreover, it is an optimal one as it has a double impact on ammonia toxicity which is a basic neurotoxin in pathogenesis of hepatic encephalopathy.
摘要
对40例失代偿期肝性脑病和中毒性肝硬化患者采用肝得健（L-鸟氨酸-L-天冬氨酸）和乳果糖（一种合成二糖）联合治疗。肝得健与乳果糖联合应用对上述患者有效。此外，它是一种最佳组合，因为它对氨毒性有双重作用，而氨毒性是肝性脑病发病机制中的一种基本神经毒素。
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