Hu Yuwen, Carpenter Jeffrey P, Cheung Albert T
Department of Anesthesiology, Division of Cardiothoracic and Vascular Anesthesia, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA.
Anesth Analg. 2002 Jul;95(1):39-41, table of contents. doi: 10.1097/00000539-200207000-00006.
Serum potassium concentration should be measured immediately before operation to detect hyperkalemia in heart failure patients treated with spironolactone. Renal insufficiency, advanced age, potassium supplementation, decompensated congestive heart failure, and a spironolactone dose larger than 25 mg/d increase the risk of hyperkalemia as a consequence of spironolactone therapy.
对于接受螺内酯治疗的心力衰竭患者，术前应立即检测血清钾浓度，以发现高钾血症。肾功能不全、高龄、补钾、失代偿性充血性心力衰竭以及螺内酯剂量大于25mg/d会增加螺内酯治疗导致高钾血症的风险。
