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危及生命的高钾血症:一名肾功能不全患者因使用螺内酯治疗心力衰竭而引发的并发症。

Life-threatening hyperkalemia: a complication of spironolactone for heart failure in a patient with renal insufficiency.

作者信息

Hu Yuwen, Carpenter Jeffrey P, Cheung Albert T

机构信息

Department of Anesthesiology, Division of Cardiothoracic and Vascular Anesthesia, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA.

出版信息

Anesth Analg. 2002 Jul;95(1):39-41, table of contents. doi: 10.1097/00000539-200207000-00006.

Abstract

Serum potassium concentration should be measured immediately before operation to detect hyperkalemia in heart failure patients treated with spironolactone. Renal insufficiency, advanced age, potassium supplementation, decompensated congestive heart failure, and a spironolactone dose larger than 25 mg/d increase the risk of hyperkalemia as a consequence of spironolactone therapy.

摘要

对于接受螺内酯治疗的心力衰竭患者,术前应立即检测血清钾浓度,以发现高钾血症。肾功能不全、高龄、补钾、失代偿性充血性心力衰竭以及螺内酯剂量大于25mg/d会增加螺内酯治疗导致高钾血症的风险。

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