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医学发病率、精神疾病和物质使用障碍。

Medical morbidity, mental illness, and substance use disorders.

作者信息

Dickey Barbara, Normand Sharon-Lise T, Weiss Roger D, Drake Robert E, Azeni Hocine

机构信息

Harvard Medical School and the Department of Psychiatry at Cambridge Hospital. Cambridge, Massachusetts 02139, USA.

出版信息

Psychiatr Serv. 2002 Jul;53(7):861-7. doi: 10.1176/appi.ps.53.7.861.

Abstract

OBJECTIVE

Previous research on the prevalence of medical disorders among adults with mental illness has been inconclusive. In general, studies have found higher rates among persons with mental illness, but these studies did not account for comorbid substance use disorders. The authors examined whether certain medical disorders are more prevalent among adults with severe mental illness and whether a comorbid substance use disorder increases prevalence beyond the effect of severe mental illness alone.

METHODS

Administrative data from the Massachusetts Division of Medical Assistance were used in a cross-sectional observational study design. The sample consisted of 26,332 Medicaid beneficiaries 18 to 64 years of age. Of these, 11,185 had been treated for severe mental illness. Twelve-month prevalence rates were computed, and logistic regression was used to estimate the effect of a substance use disorder or another mental illness on the risk of having a medical disorder.

RESULTS

Compared with Medicaid beneficiaries who were not treated for severe mental illness, those with severe mental illness had a significantly higher age- and gender-adjusted risk of the medical disorders considered in the study. Those with a comorbid substance use disorder had the highest risk for five of the disorders.

CONCLUSIONS

The higher treated prevalence of certain medical disorders among adults with severe mental illness has three implications: substance use disorder is an important risk factor and requires early detection; integration of the treatment of medical disorders and severe mental illness should receive higher priority; and efforts should be made to develop specialized disease self-management techniques.

摘要

目的

先前关于成年精神疾病患者中躯体疾病患病率的研究尚无定论。总体而言,研究发现精神疾病患者中躯体疾病的患病率较高,但这些研究未考虑合并物质使用障碍的情况。作者调查了某些躯体疾病在重度精神疾病成年患者中是否更为普遍,以及合并物质使用障碍是否会使患病率升高,且超出重度精神疾病本身的影响。

方法

在一项横断面观察性研究设计中使用了马萨诸塞州医疗救助部门的管理数据。样本包括26332名年龄在18至64岁之间的医疗补助受益 人。其中,11185人曾接受过重度精神疾病治疗。计算了12个月患病率,并使用逻辑回归来估计物质使用障碍或其他精神疾病对患躯体疾病风险的影响。

结果

与未接受重度精神疾病治疗的医疗补助受益人相比,患有重度精神疾病的患者在研究中所考虑的躯体疾病方面,经年龄和性别调整后的风险显著更高。合并物质使用障碍的患者在其中五种疾病中的风险最高。

结论

重度精神疾病成年患者中某些躯体疾病的治疗患病率较高有三个影响:物质使用障碍是一个重要的风险因素,需要早期发现;躯体疾病和重度精神疾病的治疗整合应得到更高的重视;应努力开发专门的疾病自我管理技术。

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