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成功对一名接受活体肝移植的婴儿进行经皮腔内血管成形术治疗肝动脉狭窄。

Successful percutaneous transluminal angioplasty for hepatic artery stenosis in an infant undergoing living-related liver transplantation.

作者信息

Hasegawa Toshimichi, Sasaki Takashi, Kimura Takuya, Okada Akira, Nakatsuchi Yoshiaki, Sugiura Takashi, Kato Hiromi, Nakajima Yoshikazu

机构信息

Department of Pediatric Surgery, Osaka University, Medical School, Osaka, Japan.

出版信息

Pediatr Transplant. 2002 Jun;6(3):244-8. doi: 10.1034/j.1399-3046.2002.01081.x.

Abstract

A 1-yr-old girl underwent a living-related liver transplant, with reconstruction of hepatic artery of 2 mm in diameter under microscopy. She developed intestinal perforation requiring closure on day 4 post-transplant and suffered from hepatic artery stenosis (HAS) on post-transplant day 9. Conservative therapies, such as intravenous or transluminal administration of anti-coagulants, vasodilators or fluids, were unsuccessful and caused remarkable general edema and multiple arrhythmias as a result of increased preload. On day 15 post-transplant, because flow velocity was remarkably reduced (as shown by Doppler ultrasound) the patient underwent percutaneous transluminal angioplasty (PTA) using a kit for coronary angioplasty. The balloon catheter was inflated [first: 1.5 mm diameter, 4 atmospheric pressure (a.p.) for 30 seconds (s); second: 2.0 mm diameter, 4 a.p. for 30 s; third: 2.5 mm diameter, 10 a.p. for 30 s]. The stenosis was successfully dilated without any complication. The patient has been doing well with normal liver functions for 4 months after PTA. From this experience, PTA can be performed for HAS after liver transplantation, even in an infantile case, with a careful technique and a special device.

摘要

一名1岁女童接受了亲属活体肝移植,术中在显微镜下对直径2毫米的肝动脉进行了重建。术后第4天,她出现肠道穿孔,需要进行缝合;术后第9天,又出现了肝动脉狭窄(HAS)。静脉注射或经腔给予抗凝剂、血管扩张剂或补液等保守治疗均未成功,且由于前负荷增加导致了明显的全身性水肿和多种心律失常。术后第15天,因多普勒超声显示血流速度显著降低,患者使用冠状动脉成形术套件接受了经皮腔内血管成形术(PTA)。球囊导管进行了三次扩张[第一次:直径1.5毫米,4个大气压(a.p.),持续30秒(s);第二次:直径2.0毫米,4 a.p.,持续30 s;第三次:直径2.5毫米,10 a.p.,持续30 s]。狭窄成功扩张,未出现任何并发症。PTA术后4个月,患者肝功能正常,情况良好。根据这一经验,即使是婴幼儿病例,肝移植术后发生HAS时,采用谨慎的技术和特殊装置也可进行PTA。

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