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HIV感染的皮肤表现。

The cutaneous manifestations of HIV infection.

作者信息

Garman Mary E, Tyring Stephen K

机构信息

Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.

出版信息

Dermatol Clin. 2002 Apr;20(2):193-208. doi: 10.1016/s0733-8635(01)00011-0.

Abstract

Dermatologic disease is extremely common and varied in HIV-infected patients. While some cutaneous findings are nearly exclusive to HIV-seropositive individuals, many are found in the general population. However, HIV-infected individuals often have an increased prevalence or severity, atypical presentations, or difficulty with treatment of the disease. Immune reconstitution with HAART significantly reduces the prevalence of many dermatologic diseases, but also has associated cutaneous side effects. Correct and early diagnosis of skin disease in HIV-infected individuals allows for early management and improved quality of life. Because dermatologic manifestations may be the first clue of HIV infection, offering HIV testing to affected individuals can lead to early diagnosis and treatment of HIV infection and, ideally, a decrease in disease progression and transmission.

摘要

皮肤疾病在HIV感染患者中极为常见且多种多样。虽然有些皮肤表现几乎仅见于HIV血清阳性个体,但许多也见于普通人群。然而,HIV感染个体中这些疾病的患病率或严重程度往往会增加,表现不典型,或治疗困难。高效抗逆转录病毒治疗(HAART)带来的免疫重建可显著降低许多皮肤疾病的患病率,但也会有相关的皮肤副作用。对HIV感染个体的皮肤疾病进行正确、早期诊断有助于早期管理并改善生活质量。由于皮肤表现可能是HIV感染的首个线索,对受影响个体进行HIV检测可实现HIV感染的早期诊断和治疗,理想情况下,还可减缓疾病进展并减少传播。

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