CD80 (B7-1) and CD86 (B7-2) genes and genetic susceptibility to coeliac disease.
作者信息
Woolley N, Holopainen P, Bourgain C, Mustalahti K, Collin P, Mäki M, Partanen J
机构信息
Department of Tissue Typint, finnish Red Cross Blood Transfusion Service, Helsinki, Finland.
出版信息
Eur J Immunogenet. 2002 Aug;29(4):331-3. doi: 10.1046/j.1365-2370.2002.00302.x.
Abstract
The role of the costimulatory molecules B7-1 (CD80) and B7-2 (CD86) in T-cell activation makes them good candidates for coeliac disease susceptibility genes. We conducted a genetic linkage study of the CD80/86 gene region in the general Finnish population and in a local subisolate. No linkage was found in either population.
摘要
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