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对抗生素耐药菌的管理。

Management of antibiotic-resistant bacteria.

作者信息

Norman Dean C

机构信息

VA Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA.

出版信息

J Am Geriatr Soc. 2002 Jul;50(7 Suppl):S242-6. doi: 10.1046/j.1532-5415.50.7s.5.x.

Abstract

Optimizing the management of antibiotic resistance is an important strategy in improving outcomes for infectious diseases in older persons. Strategies that manage antibiotic resistance must take into account all clinical settings, because resistant pathogens previously seen only in acute care facilities are becoming increasingly common in long-term care facilities. Recently, modest improvement in therapeutic options for the treatment of infections due to resistant pathogens has become available because of the development of newer antibiotics. Some of these drugs are briefly discussed in this review, but the best strategy is to limit the potential for the development of resistance and transmission of these pathogens. This can best be accomplished by minimizing misuse of antibiotics and maximizing adherence to basic hygiene standards.

摘要

优化抗生素耐药性管理是改善老年人传染病治疗效果的一项重要策略。管理抗生素耐药性的策略必须考虑到所有临床环境,因为以前仅在急性护理机构中出现的耐药病原体在长期护理机构中越来越常见。最近,由于新型抗生素的研发,治疗耐药病原体所致感染的治疗选择有了一定程度的改善。本综述简要讨论了其中一些药物,但最佳策略是限制这些病原体耐药性产生和传播的可能性。这可以通过尽量减少抗生素的滥用并最大限度地遵守基本卫生标准来最好地实现。

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