染色体动力学：极光激酶B功能的新见解
Chromosome dynamics: new light on Aurora B kinase function.
作者信息
Shannon Katie B, Salmon E D
机构信息
University of North Carolina, Department of Biology, 607 Fordham Hall, CB#3280, Chapel Hill 27599-3280, USA.
出版信息
Curr Biol. 2002 Jul 9;12(13):R458-60. doi: 10.1016/s0960-9822(02)00945-4.
Abstract
Aurora B family kinases play an essential role in chromosome segregation and cytokinesis. Recent work suggests that the kinase activity is required for bipolar chromosome orientation, kinetochore assembly, spindle checkpoint and microtubule dynamics. Aurora B also has additional functions in chromosome condensation and cohesion.
摘要
极光B家族激酶在染色体分离和胞质分裂中起着至关重要的作用。最近的研究表明，激酶活性对于双极染色体定向、动粒组装、纺锤体检查点和微管动力学是必需的。极光B在染色体凝聚和黏附中也具有其他功能。
Zotero 插件