杏鲍菇孢子诱发的过敏性肺炎。

Hypersensitivity pneumonitis induced by the spore of Pleurotus Eryngii (Eringi).

作者信息

Saikai Toyohiro, Tanaka Hiroshi, Fuji Masaru, Sugawara Hiroyuki, Takeya Isao, Tsunematsu Kazunori, Abe Shosaku

出版信息

Intern Med. 2002 Jul;41(7):571-3. doi: 10.2169/internalmedicine.41.571.

DOI:10.2169/internalmedicine.41.571

Abstract

We reported the first case of hypersensitivity pneumonitis (HP) by an edible mushroom, Pleurotus Eryngii (Eringi). A 54-year-old woman had worked in a Bunashimeji mushroom factory for 42 months, and she moved to a new factory producing Eringi. Two months after, she was found to have HP by the spore of Eringi. Although no radiological finding was detected 6 months before the onset of HP, serum surfactant protein D (SP-D) had been elevated. We speculated that type II pneumocyte activation might prepare the ground for HP during the former exposure to Bunashimeji, and serum SP-D levels might reflect their conditions.

摘要

我们报告了首例由食用蘑菇刺芹侧耳（杏鲍菇）引起的过敏性肺炎（HP）病例。一名54岁女性在真姬菇工厂工作了42个月，之后转到一家生产杏鲍菇的新工厂。两个月后，她被发现因杏鲍菇孢子患上了HP。尽管在HP发病前6个月未检测到影像学异常，但血清表面活性蛋白D（SP-D）水平已经升高。我们推测，在前次暴露于真姬菇期间，II型肺细胞活化可能为HP发病奠定了基础，而血清SP-D水平可能反映了这些情况。