Chacko A G, Chandy M J
Department of Neurosurgery, Christian Medical College and Hospital, Vellore, 632004, India.
Neurol India. 2002 Jun;50(2):136-40.
This study was done to determine the usefulness of the sagittal magnetic resonance image (MRI) in predicting the ease of resectability of pituitary adenomas operated through the transsphenoidal route. Tumors were graded according to Hardy's method and a new system proposed by us. In this system the amount of tumor above the line of vision (V-line) as seen on the sagittal MRI was estimated and correlated with the extent of excision assessed on the postoperative computed tomogram (CT). There were 7 Hardy's grade A (8.8%), 32 grade B (41.3%), 31 grade C (37.5%), 6 grade D (8.8%) and 2 grade E tumors (3.8%) among the 78 tumors studied. It was seen that most of the tumor volume was below the V-line in Hardy's grade A and B tumors. In grade C tumors 5 were < 25% above, 14 were 25-50% above and 12 were 50-75% above the V-line. A radical excision was possible in 15 of l9 grade C tumors in which < 50% of the tumor was above the V-line. However, only 5 of 12 with Hardy's grade C were radically excised when >50% of the tumor was above the V-line. In conclusion, Hardy's grade C tumors are not a homogenous group radiologically and using the V-line on MRI helps in predicting the case of respectability in a single stage.
本研究旨在确定矢状位磁共振成像(MRI)在预测经蝶窦入路手术切除垂体腺瘤的难易程度方面的实用性。根据Hardy方法和我们提出的新系统对肿瘤进行分级。在该系统中,评估矢状位MRI上视线上方(V线)的肿瘤量,并将其与术后计算机断层扫描(CT)评估的切除范围相关联。在所研究的78例肿瘤中,有7例Hardy A级(8.8%)、32例B级(41.3%)、31例C级(37.5%)、6例D级(8.8%)和2例E级肿瘤(3.8%)。可以看出,在Hardy A级和B级肿瘤中,大部分肿瘤体积位于V线下方。在C级肿瘤中,5例位于V线上方<25%,14例位于V线上方25%-50%,12例位于V线上方50%-75%。在19例C级肿瘤中,肿瘤位于V线上方<50%的15例能够进行根治性切除。然而,当肿瘤位于V线上方>50%时,Hardy C级的12例中只有5例进行了根治性切除。总之,Hardy C级肿瘤在放射学上不是一个同质的组,利用MRI上的V线有助于预测一期切除的可能性。