[墨西哥婴儿型大量痉挛症患儿的脑电图发现]

[Electroencephalographic discoveries in children with infantile massive spasms in Mexico].

作者信息

Alva-Moncayo E, Díaz-Leal M C, Olmos-García De Alba G

机构信息

Servicio de Neurología Pediátrica, Hospital Dr. Gaudencio González Garza. Centro Médico Nacional La Raza, México DF, México.

出版信息

Rev Neurol. 2002;34(10):928-32.

DOI:
Abstract

INTRODUCTION

Infantile massive spasms (IMS) is an age dependent epileptic syndrome that appears before the first year, and is characterised by delayed psychomotor development, massive spasms and hypsarrhythmia. There are classifications that only take the electroencephalogram (EEG) into account, without linking it with the IMS associated crisis pattern which can establish a treatment to improve the recurrence of the crises in this population, according to EEG discoveries and patterns of epileptic fits.

PATIENTS AND METHODS

We include 100 EEGs of patients diagnosed with IMS, between 2 and 12 months old, selected by using the classification of Hrachovy to identify classic and modified hypsarrhythmia, and to correlate it with the pattern of epileptic seizures associated with IMS.

RESULTS

The hypsarrhythmia found was mainly of the modified variety, and classic hypsarrhythmia only accounted for 9% of cases. The first case presented flexion IMS with generalised tonic seizures, and in the second, generalised tonic seizures and mixed IMS. Start age was between 2 and 4 months old.

CONCLUSIONS

In comparison with results in other publications, in the EEG it was found that modified hypsarrhythmia with IMS associated partial and generalised tonic seizures with was the most common, while in the classic variety mixed IMS predominated. It must be taken into account that the absence of this variety does not rule out a diagnosis of IMS, but its presence makes the prognosis worse.

摘要

引言

婴儿痉挛症(IMS)是一种发生在一岁前的年龄依赖性癫痫综合征,其特征为精神运动发育迟缓、痉挛发作和高度节律失调。有些分类仅考虑脑电图(EEG),但未将其与IMS相关的发作模式联系起来,而根据脑电图发现和癫痫发作模式,这种发作模式可确立改善该人群发作复发情况的治疗方法。

患者与方法

我们纳入了100例年龄在2至12个月、被诊断为IMS的患者的脑电图,通过使用赫拉乔维(Hrachovy)分类法来识别典型和改良型高度节律失调,并将其与IMS相关的癫痫发作模式相关联。

结果

发现的高度节律失调主要为改良型,典型高度节律失调仅占病例的9%。第一例表现为伴有全身性强直发作的屈曲型IMS,第二例为全身性强直发作和混合型IMS。发病年龄在2至4个月之间。

结论

与其他出版物的结果相比,在脑电图中发现,伴有IMS相关部分性和全身性强直发作的改良型高度节律失调最为常见,而在典型类型中,混合型IMS占主导。必须考虑到,这种类型的缺失并不排除IMS的诊断,但它的存在会使预后更差。

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