球后注射氯丙嗪用于治疗失明和有视觉的疼痛性眼睛。
Retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes.
作者信息
Chen Teresa C, Ahn Yuen Sonia J, Sangalang Marither A, Fernando Ronaldo E, Leuenberger Edgar U
机构信息
Glaucoma Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
出版信息
J Glaucoma. 2002 Jun;11(3):209-13. doi: 10.1097/00061198-200206000-00008.
PURPOSE
To report the efficacy of primary retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes.
PATIENTS AND METHODS
Retrospective case series from three university hospitals was done. Twenty eyes of 20 patients with at least 3 months of follow-up are reported. Ten of these 20 eyes did not receive any other ophthalmic medications either 2 weeks before chlorpromazine injection or at any time point after injection. Treatment was considered successful if pain control lasted for at least 3 months, without the need for reinjection or enucleation.
RESULTS
Sixteen of 20 (80.0%) eyes achieved successful pain control. There were no permanent complications in any patient.
CONCLUSIONS
Retrobulbar chlorpromazine appears to be safe and effective for the management of pain in blind eyes.
目的
报告原发性球后注射氯丙嗪治疗失明和有视力的疼痛性眼睛的疗效。
患者和方法
对三家大学医院进行回顾性病例系列研究。报告了20例患者的20只眼睛，至少随访3个月。这20只眼睛中有10只在注射氯丙嗪前2周或注射后的任何时间点均未接受任何其他眼科药物治疗。如果疼痛控制持续至少3个月，且无需再次注射或眼球摘除，则认为治疗成功。
结果
20只眼睛中有16只（80.0%）实现了成功的疼痛控制。所有患者均无永久性并发症。
结论
球后注射氯丙嗪似乎对治疗失明眼睛的疼痛安全有效。
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