Mitomycin C as adjunct therapy in correcting punctal stenosis.
作者信息
Ma'luf Riad N, Hamush Nicolas G, Awwad Shady T, Noureddin Baha' N
机构信息
Department of Ophthalmology, American University of Beirut-Medical Center, Beirut, Lebanon.
出版信息
Ophthalmic Plast Reconstr Surg. 2002 Jul;18(4):285-8. doi: 10.1097/00002341-200207000-00010.
PURPOSE
To assess the efficacy of intraoperative mitomycin C in improving the success rate of the posterior punctectomy procedure.
METHODS
The charts of all patients who underwent posterior punctectomy between the years 1997 and 2000 were reviewed. The procedure was done without mitomycin C (n = 26 eyes, group A) until the end of 1998 and with mitomycin C (n = 25 eyes, group B) starting in 1999. The Kaplan-Meier curve was used for statistical evaluation.
RESULTS
In group A, 5 of 26 (19.2%) eyes had complete anatomic obstruction and scarring of their puncta after surgery, compared with 0 of 25 (0.0%) eyes in group B. The difference was statistically significant (P<0.02). No significant complications were observed.
CONCLUSIONS
Mitomycin C appears to be a safe and effective adjunct therapy in correcting punctal stenosis.
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