帽状结构：前核糖体RNA的5'端被U3小核仁核糖核蛋白修饰。

Sno-capped: 5' ends of preribosomal RNAs are decorated with a U3 SnoRNP.

作者信息

Culver Gloria M

机构信息

Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.

出版信息

Chem Biol. 2002 Jul;9(7):777-9. doi: 10.1016/s1074-5521(02)00171-0.

DOI:10.1016/s1074-5521(02)00171-0

PMID:12144919

Abstract

Efficient ribosome biosynthesis is crucial for cell viability. Work recently published in Nature demonstrates that a large ribonucleoprotein processes 18S rRNA in S. cerevisiae, indicating that macromolecular particles regulate ribosome maturation and revealing the complex nature of this process.

摘要

高效的核糖体生物合成对细胞活力至关重要。最近发表在《自然》杂志上的研究表明，一种大型核糖核蛋白对酿酒酵母中的18S rRNA进行加工，这表明大分子颗粒调节核糖体成熟，并揭示了这一过程的复杂性。