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有症状胆结石的磁共振胰胆管造影:根据临床风险组别的诊断准确性

MR cholangiography in symptomatic gallstones: diagnostic accuracy according to clinical risk group.

作者信息

Kim Joo Hee, Kim Myeong-Jin, Park Sung Il, Chung Jae-Joon, Song Si Young, Kim Kyung Sik, Yoo Hyung Sik, Lee Jong Tae, Kim Ki Whang

机构信息

Department of Diagnostic Radiology, Yonsei University College of Medicine, Seodaemun-ku Shinchon-dong 134, Seoul 120-752, Korea.

出版信息

Radiology. 2002 Aug;224(2):410-6. doi: 10.1148/radiol.2241011223.

Abstract

PURPOSE

To determine the diagnostic accuracy of magnetic resonance (MR) cholangiography in the detection of common bile duct (CBD) stones in patients with symptomatic gallstones.

MATERIALS AND METHODS

Single-shot half-Fourier MR cholangiographic images were obtained in 121 consecutive patients who were referred for MR cholangiography prior to cholecystectomy for symptomatic gallstones. One radiologist interpreted the MR cholangiographic images without prior knowledge of laboratory test results or findings from examinations with other imaging modalities. Patients were retrospectively divided into three groups with high, moderate, and low risk (n = 70, 22, and 29, respectively) for CBD stones. The sensitivity, specificity, and accuracy of MR cholangiography in the detection of CBD stones in each group were calculated. The accuracy of laboratory and sonographic findings in the identification of CBD stones was also calculated.

RESULTS

CBD stones were diagnosed in 49 (70%) of 70 patients in the high-risk group. One false-positive diagnosis was made, and two false-negative diagnoses were made. Of the 22 patients in the moderate-risk group, seven (32%) had CBD stones, and there was one false-positive and one false-negative diagnosis. In the low-risk group, CBD stones were correctly identified with MR cholangiography in one patient, and there was one false-positive diagnosis. A combination of positive laboratory and sonographic findings yielded a sensitivity of 98% but a specificity of only 34% if any unusual finding in any one of the tests was regarded as a positive finding.

CONCLUSION

MR cholangiography is highly accurate in the detection of CBD stones in all patients, regardless of the grade of risk, and should be considered in patients with a moderate to high risk of CBD stones before cholecystectomy.

摘要

目的

确定磁共振(MR)胆管造影术对有症状胆结石患者胆总管(CBD)结石的诊断准确性。

材料与方法

对121例因有症状胆结石行胆囊切除术而接受MR胆管造影检查的连续患者,获取单次激发半傅里叶MR胆管造影图像。一名放射科医生在不了解实验室检查结果或其他影像学检查结果的情况下解读MR胆管造影图像。患者被回顾性分为胆总管结石高、中、低风险三组(分别为n = 70、22和29)。计算每组中MR胆管造影术检测胆总管结石的敏感性、特异性和准确性。还计算了实验室检查和超声检查结果在识别胆总管结石方面的准确性。

结果

高风险组70例患者中有49例(70%)诊断为胆总管结石。有1例假阳性诊断和2例假阴性诊断。中风险组22例患者中,7例(32%)有胆总管结石,有1例假阳性和1例假阴性诊断。在低风险组中,MR胆管造影正确识别出1例胆总管结石,有1例假阳性诊断。如果将任何一项检查中的任何异常发现视为阳性结果,实验室检查和超声检查结果阳性相结合时,敏感性为98%,但特异性仅为34%。

结论

无论风险等级如何,MR胆管造影术对所有患者胆总管结石的检测都具有高度准确性,对于有中度至高度胆总管结石风险的患者,在胆囊切除术前应考虑采用该检查。

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