Dickinson Hugh, Scott Rod
Department of Plant Sciences, University of Oxford, South Parks Road, United Kingdom.
Mol Cell. 2002 Jul;10(1):5-7. doi: 10.1016/s1097-2765(02)00582-8.
Parental imprinting regulates processes as diverse as mammalian development and seed size in crop plants. In Arabidopsis, the DNA glycosylase DEMETER regulates early seed development, through activation of the maternal copy of the imprinted MEDEA Polycomb gene. Paternal silencing of MEA appears to be a default condition.
亲本印记调控着从哺乳动物发育到作物种子大小等多种不同的过程。在拟南芥中,DNA糖基化酶DEMETER通过激活印记基因MEDEA多梳基因的母本拷贝来调控早期种子发育。MEA的父本沉默似乎是一种默认状态。