German Igor, Lantsberg Sophia, Crystal Pavel, Assali Murad, Rachinsky Irina, Kaneti Jacob, Neulander Endre
Department of Urology, Faculty of the Health Sciences, Soroka University Medical Center, Ben Gurion University, P.O. Box 151, 84101, Beer Sheva, Israel.
Eur Urol. 2002 Aug;42(2):188-91. doi: 10.1016/s0302-2838(02)00271-3.
To determine the value of the combined use of non contrast computerized tomography (NCCT) and dynamic renal scintigraphy (DRS) in the evaluation of patients with renal colic.
Forty-nine consecutive patients with renal colic were evaluated with abdominal plain films (KUB), NCCT and DRS with Tc-99m DTPA or MAG-3. NCCT results showed size and location of the urolithiasis, as well as secondary signs of obstruction. DRS was used to determine the degree of obstruction in the affected renal unit. Patients were submitted to urologic intervention or followed, decision made on the basis of clinical symptoms, degree of obstruction, size, and location of the stone.
Three patients had other etiologies than stone for their symptoms and were excluded from the study. Of the remaining 46 patients, KUB detected stones in 24 (52.2%), while NCCT in all. NCCT showed secondary signs of obstruction in 35 patients (76%). Seven patients in this group (15%) had severe hydronephrosis on NCCT and complete obstruction on DRS. Twenty-eight patients (61%) showed moderate hydronephrosis and/or peri-renal and peri-ureteral stranding on the NCCT. In this latter group, DRS diagnosed complete obstruction in 5 (18%) patients, partial obstruction in 16 (57%) and no signs of obstruction in 7 (25%) patients. Overall 34% (12/35) of the patients with secondary signs of obstruction on NCCT had complete obstruction on DRS. NCCT revealed no secondary signs of obstruction in 11 patients (24%) with partial obstruction diagnosed by DRS in one of them (9%). All 12 patients with complete obstruction on the DRS underwent early intervention. Of the 16 patients with partial obstruction of the DRS, two patients (12.5%) necessitated ureteric stent insertion. Three patients with no obstruction on the RNS underwent elective extracorporal shock wave lithotripsy (ESWL) while the rest of the patients were followed and passed their stones spontaneously.
The combination of non-enhanced helical CT and DRS assesses both anatomy and function. When NCCT shows no secondary signs of obstruction, NCCT as the sole imaging study performed may be adequate. If there are secondary signs of obstruction on NCCT, DRS can distinguish patients with different degrees of obstruction and together with the clinical course, size, and location of the lithiasis may help in selecting patients who need earlier intervention from those who may be safely observed.
确定非增强计算机断层扫描(NCCT)和动态肾闪烁显像(DRS)联合使用在评估肾绞痛患者中的价值。
对49例连续的肾绞痛患者进行腹部平片(KUB)、NCCT以及使用锝-99m二乙三胺五乙酸(DTPA)或巯基乙酰三甘氨酸(MAG-3)的DRS检查。NCCT结果显示尿路结石的大小和位置以及梗阻的继发征象。DRS用于确定患肾单位的梗阻程度。根据临床症状、梗阻程度、结石大小和位置,对患者进行泌尿外科干预或随访观察。
3例患者症状的病因并非结石,被排除在研究之外。在其余46例患者中,KUB检测到结石24例(52.2%),而NCCT检测到所有结石。NCCT显示35例患者(76%)有梗阻的继发征象。该组中有7例患者(15%)在NCCT上显示重度肾积水,在DRS上显示完全梗阻。28例患者(61%)在NCCT上显示中度肾积水和/或肾周及输尿管周围条索状影。在这后一组中,DRS诊断5例患者(18%)为完全梗阻,16例患者(57%)为部分梗阻,7例患者(25%)无梗阻征象。总体而言,NCCT上有梗阻继发征象的患者中34%(12/35)在DRS上为完全梗阻。NCCT显示11例患者(24%)无梗阻继发征象,其中1例(9%)在DRS上诊断为部分梗阻。DRS上显示完全梗阻的12例患者均接受了早期干预。DRS上显示部分梗阻的16例患者中,2例患者(12.5%)需要插入输尿管支架。3例RNS上无梗阻的患者接受了选择性体外冲击波碎石术(ESWL),其余患者进行随访观察,结石自行排出。
非增强螺旋CT和DRS联合使用可评估解剖结构和功能。当NCCT未显示梗阻继发征象时,仅进行NCCT作为唯一的影像学检查可能就足够了。如果NCCT上有梗阻继发征象,DRS可区分不同梗阻程度的患者,结合临床病程、结石大小和位置,可能有助于从可安全观察的患者中选择需要早期干预的患者。