Lee Jong Soo, Choi Young Rac, Lee Ji Eun, Choi Hee Young, Lee Sang Hyup, Oum Boo Sup
Department of Ophthalmology, College of Medicine, Pusan National University, Korea.
Korean J Ophthalmol. 2002 Jun;16(1):13-9. doi: 10.3341/kjo.2002.16.1.13.
This study examined the influence of age, sex, blood pressure, and obesity index on intraocular pressure (IOP), in order to investigate the relationship between the upper limits of the following two conditions in the general Korean population: the "systolic or diastolic hypertensive and obese" group and the "systolic or diastolic hypotensive and lean" group. A total of 6828 healthy subjects (13,656 eyes) underwent automated multi-phasic tests, including tonometry, blood pressure, visual field, and body mass index. The 6,828 subjects were divided into five groups based on age; less than 40, 40 to 49, 50 to 59, 60 to 69, and over 70 years old. They were also divided into four categories on the basis of sex, age, blood pressure, and obesity index. The mean IOP in males (15.8+/-3.3 mmHg) was significantly higher than in females (14.8+/-3.1 mmHg) (P < 0.05), but this difference decreased proportionally with increasing age. IOP had a tendency to decrease with increasing age (P < 0.05). IOP increased significantly with increasing systolic blood pressure, diastolic blood pressure and obesity index (all, P < 0.05). The mean IOP of the "systolic or diastolic hypertensive and obese" group was higher than that of the "systolic or diastolic hypotensive and lean" group in the general Korean population (P < 0.05). These data could aid investigation into the epidemiological, etiologic and oriental influences related to the risk factors of glaucoma, especially in oriental populations.
本研究探讨年龄、性别、血压和肥胖指数对眼压(IOP)的影响,以调查韩国普通人群中“收缩压或舒张压高血压且肥胖”组与“收缩压或舒张压低血压且消瘦”组这两种情况上限之间的关系。共有6828名健康受试者(13656只眼)接受了自动多相检查,包括眼压测量、血压、视野和体重指数。6828名受试者根据年龄分为五组:小于40岁、40至49岁、50至59岁、60至69岁和70岁以上。他们还根据性别、年龄、血压和肥胖指数分为四类。男性的平均眼压(15.8±3.3 mmHg)显著高于女性(14.8±3.1 mmHg)(P<0.05),但这种差异随年龄增长成比例减小。眼压有随年龄增长而降低的趋势(P<0.05)。眼压随收缩压、舒张压和肥胖指数的增加而显著升高(均P<0.05)。在韩国普通人群中,“收缩压或舒张压高血压且肥胖”组的平均眼压高于“收缩压或舒张压低血压且消瘦”组(P<0.05)。这些数据有助于调查与青光眼危险因素相关的流行病学、病因学和东方影响因素,尤其是在东方人群中。