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[十二烷基硫酸钠对动物组织脱氧核糖核酸酶的抑制作用]

[Inhibiting effect of sodium dodecylsulphate on DNase of animal tissues].

作者信息

Rysina T N

出版信息

Ukr Biokhim Zh. 1975 May-Jun;47(3):332-4.

PMID:1216348
Abstract

The activity of DNases in homogenates of the spleen, thyroid gland and intestine mucosa of rats as well as in solution of purified pancreatic DNase was studied as affected by sodium dodecylsulphate. Dodecylsulphate has an inhibitory effect on all the studied DNase. The effect grows up to complete inhibition of DNases with an increase in the content of detergent in the incubation mixture from 0.5 to 5-10 mg/ml.

摘要

研究了十二烷基硫酸钠对大鼠脾脏、甲状腺和肠黏膜匀浆中脱氧核糖核酸酶(DNases)活性以及纯化胰脱氧核糖核酸酶溶液中该酶活性的影响。十二烷基硫酸钠对所有研究的脱氧核糖核酸酶均有抑制作用。随着孵育混合物中去污剂含量从0.5毫克/毫升增加到5 - 10毫克/毫升,这种抑制作用增强,直至完全抑制脱氧核糖核酸酶的活性。

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