[髓母细胞瘤和室管膜瘤的神经放射学鉴别诊断：HIT'91研究结果]
[Neuroradiological differential diagnosis in medulloblastomas and ependymomas: results of the HIT'91-study].
作者信息
Warmuth-Metz M, Kühl J
机构信息
Abteilung für Neuroradiologie, Universität Würzburg, Germany.
出版信息
Klin Padiatr. 2002 Jul-Aug;214(4):162-6. doi: 10.1055/s-2002-33190.
BACKGROUND
Imaging criteria of medulloblastomas and ependymomas were defined retrospectively to allow a preoperative differential diagnosis of these malignant tumors of the posterior fossa.
PATIENTS AND METHODS
CT and/or MR-studies of 103 patients with medulloblastomas and 19 ependymomas treated in the HIT'91-trial were centrally reviewed. Evaluation concerned the origin, CT-density or MR-signal intensity, enhancement, internal structural homogeneity and results of staging of the tumors.
RESULTS
Medulloblastomas and Ependymomas showed different results concerning all imaging criteria.
CONCLUSION
On the basis of differences in localisation, enhancement and tumor growth in most cases a preoperative differential diagnosis between medulloblastomas and ependymomas is possible. Increased density on CT allows the differentiation of the malignant tumors from pilocytic astrocytomas of the fourth ventricle.
背景
髓母细胞瘤和室管膜瘤的影像学标准是通过回顾性定义的，以便对这些后颅窝恶性肿瘤进行术前鉴别诊断。
患者与方法
对在HIT'91试验中接受治疗的103例髓母细胞瘤患者和19例室管膜瘤患者的CT和/或磁共振成像研究进行了集中回顾。评估内容包括肿瘤的起源、CT密度或磁共振信号强度、强化情况、内部结构均匀性以及分期结果。
结果
髓母细胞瘤和室管膜瘤在所有影像学标准方面均表现出不同的结果。
结论
基于定位、强化和肿瘤生长方面的差异，在大多数情况下，术前对髓母细胞瘤和室管膜瘤进行鉴别诊断是可行的。CT上密度增加有助于将这些恶性肿瘤与第四脑室的毛细胞型星形细胞瘤区分开来。
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