Jayaram G, Dashini M
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Malays J Pathol. 2001 Dec;23(2):93-100.
141 salivary gland lesions that were subjected to fine needle aspiration (FNA) cytology at the University Hospital, Kuala Lumpur, from January 1993 to October 2000 were reviewed with a view to assess the sensitivity and utility of cytological diagnosis in diseases of salivary glands. The highest number of cases was seen in the sixth decade of life. There was no gender preponderance in salivary gland neoplasms except in Warthin's tumours that occurred predominantly in males. The parotid gland was the most frequent salivary gland needled. Seven cases (5%) presented with bilateral salivary gland enlargement. Cytological study yielded a neoplastic diagnosis in 74.5% cases. Of the neoplastic lesions, 71.4% could be definitely designated as benign and 25.7% as clearly malignant. Pleomorphic adenoma and acinic cell carcinoma were the most common benign and malignant neoplasms diagnosed respectively. 53 cases had histological correlation; of these, 49 (92.5%) were neoplastic. The overall diagnostic accuracy of FNA cytological diagnosis in salivary gland lesions was found to be 73.6%.
对1993年1月至2000年10月间在吉隆坡大学医院接受细针穿刺(FNA)细胞学检查的141例唾液腺病变进行了回顾,以评估细胞学诊断在唾液腺疾病中的敏感性和实用性。病例数最多的出现在60岁年龄段。除了主要发生在男性的沃辛瘤外,唾液腺肿瘤在性别上无明显优势。腮腺是最常接受穿刺的唾液腺。7例(5%)表现为双侧唾液腺肿大。细胞学研究在74.5%的病例中得出肿瘤性诊断。在肿瘤性病变中,71.4%可明确诊断为良性,25.7%为明显恶性。多形性腺瘤和腺泡细胞癌分别是最常见的诊断出的良性和恶性肿瘤。53例有组织学对照;其中49例(92.5%)为肿瘤性病变。FNA细胞学诊断唾液腺病变的总体诊断准确性为73.6%。