van de Geijn E J, Lemij H G, de Vries J, de Waard P W T
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, the Netherlands.
J Glaucoma. 2002 Aug;11(4):300-5. doi: 10.1097/00061198-200208000-00005.
To assess the clinical outcome of one technique for surgical revision of filtration blebs in terms of bleb function and intraocular pressure control.
Retrospective analysis of 36 consecutive cases of leaking, overfiltrating, or oversized blebs treated with bleb excision and conjunctiva and Tenon advancement in a glaucoma referral center between January 1991 and December 1999. Surgical success was defined as a final intraocular pressure between 6 and 22 mm Hg with or without topical antiglaucoma medication, resolution of the bleb leak, hypotony maculopathy and symptoms, and no need for repeat glaucoma surgery.
With a minimum of 12 months and an average of 29.5 months of follow-up, the overall success rate was 86.1%, with 51.6% of patients not requiring medication. In the success group, mean (SD) intraocular pressure was 23.7 (5.9) mm Hg before the original trabeculectomy, 4.3 (3.7) mm Hg prior to revision surgery, and 13.5 (SD 3.8) mm Hg at the last follow-up visit after the revision surgery. Mean number of antiglaucoma medications was 2.1 (range, 1-4) before the original trabeculectomy, none before the revision surgery, and 0.8 (range, 0-3) at the last follow-up visit.
The surgical revision technique offers a definitive solution for most of these bleb complications and a satisfactory intraocular pressure control in the majority of patients.
从滤过泡功能和眼压控制方面评估一种滤过泡手术修复技术的临床效果。
回顾性分析1991年1月至1999年12月间在一家青光眼转诊中心连续36例接受滤过泡切除术、结膜和眼球筋膜推进术治疗的渗漏、滤过过度或过大滤过泡病例。手术成功定义为最终眼压在6至22 mmHg之间,无论是否使用局部抗青光眼药物,滤过泡渗漏、低眼压性黄斑病变和症状均得到缓解,且无需再次进行青光眼手术。
随访时间最短12个月,平均29.5个月,总体成功率为86.1%,51.6%的患者无需用药。在成功组中,初次小梁切除术前平均(标准差)眼压为23.7(5.9)mmHg,修复手术前为4.3(3.7)mmHg,修复手术后最后一次随访时为13.5(标准差3.8)mmHg。初次小梁切除术前抗青光眼药物平均使用数量为2.1(范围1 - 4),修复手术前无需用药,最后一次随访时为0.8(范围0 - 3)。
该手术修复技术为大多数此类滤过泡并发症提供了确切的解决方案,并且在大多数患者中能实现令人满意的眼压控制。