Lorentz Cindy Pham, Wieben Eric D, Tefferi Ayale, Whiteman David A H, Dewald Gordon W
Division of Laboratory Genetics, Mayo Clinic, Rochester, Minn 55905, USA.
Mayo Clin Proc. 2002 Aug;77(8):773-82. doi: 10.4065/77.8.773.
In comparison with most other disciplines of science, the field of genetics is still in its youth. The majority of scientific work in genetics has been done in the past 150 years. The successful preliminary sequencing of the human genome was announced in 2001. Nonetheless, interest in heredity and in other concepts within the field of genetics has existed since the beginning of humanity. This article provides an account of the history of genetics, spanning from humankind's initial attempts to understand and influence heredity, to the early scientific work in the field of genetics, and subsequently to the advancements in modern genetics. Additionally, the Human Genome Project is summarized, from inception to publication of the 'first draft" of the human genome sequence.
与大多其他科学学科相比,遗传学领域仍处于起步阶段。遗传学领域的大部分科学工作是在过去150年完成的。2001年宣布了人类基因组的成功初步测序。尽管如此,自人类伊始,人们就对遗传学领域的遗传及其他概念产生了兴趣。本文讲述了遗传学的历史,涵盖了人类最初试图理解和影响遗传的尝试,到遗传学领域的早期科学工作,以及随后现代遗传学的进展。此外,还总结了人类基因组计划,从其启动到人类基因组序列“初稿”的发表。