肠道细菌中的汞抗性（mer）操纵子。

Mercury resistance (mer) operons in enterobacteria.

作者信息

Hobman J L, Essa A M M, Brown N L

机构信息

School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

出版信息

Biochem Soc Trans. 2002 Aug;30(4):719-22. doi: 10.1042/bst0300719.

DOI:10.1042/bst0300719

PMID:12196175

Abstract

Mercury resistance is found in many genera of bacteria. Common amongst enterobacteria are transposons related to Tn21, which is both mercuric ion- and streptomycin-/spectinomycin- and sulphonamide-resistant. Other Tn21-related transposons often have different antibiotic resistances compared with Tn21, but share many non-antibiotic-resistance genes with it. In this article we discuss possible mechanisms for the evolution of Tn21 and related genetic elements.

摘要

许多细菌属中都发现了汞抗性。肠杆菌中常见的是与Tn21相关的转座子，它对汞离子、链霉素/壮观霉素和磺胺类药物都具有抗性。与Tn21相关的其他转座子通常与Tn21相比具有不同的抗生素抗性，但与之共享许多非抗生素抗性基因。在本文中，我们讨论了Tn21及相关遗传元件进化的可能机制。