Besada Eulogio, Woods Albert, Caputo Michelle
College of Optometry, NOVA Southeastern University, North Miami Beach, Florida 33162, USA.
Optom Vis Sci. 2002 Aug;79(8):479-88. doi: 10.1097/00006324-200208000-00009.
This article documents a case of neuroretinitis initially presenting with ocular pain, 20/20 visual acuities, optic disc edema, and macular serous detachment without macular star formation in the absence of a history of exposure to pets or cats or symptoms suggestive of Bartonella infection. This initial clinical presentation appeared unilateral, but later became bilateral.
Physical and neuroophthalmologic consultation, neuroimaging studies, blood chemistry, and serologic analysis were requested. Positive serologic (IGG) titers to Bartonella henselae and Bartonella quintana were detected. Treatment was instituted initially with oral tetracycline (250 mg) qid and subsequently with doxycycline (100 mg) bid and prednisone (20 mg) qd.
Bartonella infection may cause optic disc edema and serous detachment without macular star formation. This presentation may occur without the generally characteristic signs and symptoms of Bartonella-associated neuroretinitis. A bilateral involvement may follow an initial unilateral presentation during the affliction period of this disorder.
本文记录了一例神经视网膜炎病例,该病例最初表现为眼痛、视力20/20、视盘水肿和黄斑浆液性脱离,无黄斑星芒状渗出,且无接触宠物或猫的病史或提示巴尔通体感染的症状。这种初始临床表现起初为单侧,但后来发展为双侧。
进行了体格检查和神经眼科会诊,并要求进行神经影像学检查、血液化学检查和血清学分析。检测到针对汉赛巴尔通体和五日热巴尔通体的血清学(IgG)滴度呈阳性。最初给予口服四环素(250毫克)每日四次治疗,随后给予强力霉素(100毫克)每日两次和泼尼松(20毫克)每日一次治疗。
巴尔通体感染可能导致视盘水肿和浆液性脱离,而无黄斑星芒状渗出。这种表现可能在没有巴尔通体相关性神经视网膜炎通常特征性体征和症状的情况下出现。在该疾病的患病期间,初始单侧表现之后可能会出现双侧受累。