Watkins Ryan, Vyas Harish
Department of Child Health, University Hospital, Nottingham NG7 2UH, UK.
Eur J Pediatr. 2002 Sep;161(9):497-8. doi: 10.1007/s00431-002-1032-7. Epub 2002 Aug 13.
Group A streptococcal (GAS) infection is the most common cause of bacterial pharyngitis and has an important role in the pathogenesis of post-infective phenomena including rheumatic fever and glomerulonephritis. Mortality from GAS is uncommon, particularly in the paediatric population. Toxic shock syndrome reflects the most severe form of GAS-related disease and is often associated with fasciitis or myositis.
We present three cases of toxic shock syndrome secondary to (GAS) myositis demonstrating the importance of early recognition and provision of intensive care management.
A 组链球菌(GAS)感染是细菌性咽炎最常见的病因,在包括风湿热和肾小球肾炎在内的感染后现象的发病机制中起重要作用。GAS 导致的死亡并不常见,尤其是在儿科人群中。中毒性休克综合征是 GAS 相关疾病最严重的形式,常与筋膜炎或肌炎相关。
我们报告了 3 例继发于 GAS 肌炎的中毒性休克综合征病例,证明了早期识别和提供重症监护管理的重要性。