Tsutsumi Masanori, Kazekawa Kiyoshi, Tanaka Akira, Ueno Yasushi, Nomoto Yasuyuki, Nii Kohei, Haraoka Seiji
Department of Neurosurgery, Fukuoka University Chikushi Hospital, Chikushino, Japan.
Neurol Med Chir (Tokyo). 2002 Aug;42(8):338-40. doi: 10.2176/nmc.42.338.
A 62-year-old man with neurofibromatosis type 1 presented with rapid growth of a scalp mass. Head computed tomography demonstrated a large extracranial tumor of soft tissue density with massive intratumoral hematoma. Cerebral angiography demonstrated remarkable hypervascularity of the tumor. Preoperative embolization and total removal of the tumor was performed. The tumor contained a large amount of intratumoral hematoma (500 ml). The histological diagnosis was neurofibroma without malignant transformation. Benign scalp neurofibroma showing massive intratumoral hemorrhage is rare. Rapid growth or intratumoral hemorrhage in neurofibroma may be an indicator of malignant transformation.
一名患有1型神经纤维瘤病的62岁男性出现头皮肿物迅速生长。头部计算机断层扫描显示一个巨大的颅外软组织密度肿瘤，伴有大量瘤内血肿。脑血管造影显示肿瘤有明显的血管增多。进行了术前栓塞和肿瘤全切术。肿瘤含有大量瘤内血肿（500毫升）。组织学诊断为无恶性转化的神经纤维瘤。表现为大量瘤内出血的良性头皮神经纤维瘤很罕见。神经纤维瘤的快速生长或瘤内出血可能是恶性转化的一个指标。
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