Matsumoto Kenichi, Nakagaki Hiroyuki
Department of Neuropathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Neurol Med Chir (Tokyo). 2002 Aug;42(8):349-53. doi: 10.2176/nmc.42.349.
A 37-year-old female presented with a rare spinal subependymoma manifesting as progressive weakness of her right lower extremity over an 8-month period. She had a 10-year history of back pain and urinary disturbance. Magnetic resonance imaging showed diffuse enlargement of the spinal cord from T-2 to T-7 on the T1-weighted images. The enlarged spinal cord was divided into two compartments by a vertical septum-like structure on the T2-weighted images. The tumor occupied the right half of the thoracic spinal cord, and was totally removed through a laminectomy from T-2 to T-7. The histological diagnosis of the resected specimen was subependymoma. Subependymomas are slow-growing tumors usually found in the ventricular system. Spinal subependymomas are difficult to distinguish from other intramedullary spinal tumors based on neuroradiological findings. Subependymomas are surgically curable tumors, so if the tumor is well demarcated and a subependymoma is indicated, an attempt should be made to totally remove the tumor.
一名37岁女性因罕见的脊髓室管膜下瘤就诊,在8个月的时间里表现为右下肢进行性无力。她有10年的背痛和排尿障碍病史。磁共振成像显示,在T1加权图像上,脊髓从T2到T7弥漫性增大。在T2加权图像上,增大的脊髓被一个垂直的间隔样结构分成两个部分。肿瘤占据胸段脊髓的右半部分,并通过T2至T7椎板切除术完全切除。切除标本的组织学诊断为室管膜下瘤。室管膜下瘤是生长缓慢的肿瘤,通常见于脑室系统。基于神经放射学表现,脊髓室管膜下瘤很难与其他脊髓髓内肿瘤区分开来。室管膜下瘤是可通过手术治愈的肿瘤,因此,如果肿瘤边界清晰且提示为室管膜下瘤,应尝试完全切除肿瘤。