Hellström-Westas L, Blennow G, Rosén I
Department of Paediatrics, University Hospital, Lund, Sweden.
Acta Paediatr. 2002;91(8):977-80. doi: 10.1080/080352502760148748.
Pyridoxine-dependent seizures are rare in newborn infants, although recent data suggest that the prevalence probably is underestimated. In all newborn infants with recurrent epileptic seizures the general recommendation is to administer pyridoxine and simultaneously record an electroencephalogram (EEG).
One infant with pyridoxine-responsive seizures and another with pyridoxine-dependent seizures had different electroclinical responses on amplitude-integrated EEG monitoring (aEEG) when pyridoxine was administered.
维生素B6依赖型癫痫在新生儿中很少见,尽管近期数据表明其患病率可能被低估。对于所有反复发生癫痫发作的新生儿,一般建议给予维生素B6并同时记录脑电图(EEG)。
在给予维生素B6时,一名维生素B6反应性癫痫婴儿和另一名维生素B6依赖型癫痫婴儿在振幅整合脑电图监测(aEEG)上有不同的电临床反应。