Bartlett John G, Inglesby Thomas V, Borio Luciana
Johns Hopkins University Center for Civilian Biodefense Strategies, Johns Hopkins University School of Medicine, Baltimore, MD 21287-0003, USA.
Clin Infect Dis. 2002 Oct 1;35(7):851-8. doi: 10.1086/341902. Epub 2002 Aug 30.
From 3 October 2001 through 16 November 2001, in the United States, there were 18 confirmed cases of inhalational and cutaneous anthrax, an additional 4 suspected cases of cutaneous anthrax, and 5 deaths due to inhalational anthrax. Although the number of cases was relatively small, this experience brought bioterrorism and its potential to sharp focus as thousands of people began receiving prophylactic antibiotics after possible exposure to anthrax spores. These events have resulted in a substantial impact on the health care system, including the rewriting of pneumonia guidelines, new emphasis on identification of microbial etiology, substantial infusion of funds for bioterrorism-related research, and a sudden mandate for regional disaster and public health planning. This article provides clinicians with clinically relevant information about the diagnosis and management of anthrax.
从2001年10月3日至2001年11月16日,在美国,有18例吸入性和皮肤炭疽确诊病例,另外还有4例疑似皮肤炭疽病例,以及5例因吸入性炭疽死亡的病例。尽管病例数量相对较少,但随着数千人在可能接触炭疽孢子后开始接受预防性抗生素治疗,这一事件使生物恐怖主义及其潜在影响成为人们高度关注的焦点。这些事件对医疗保健系统产生了重大影响,包括重新编写肺炎指南、重新强调微生物病因的识别、大量注入与生物恐怖主义相关的研究资金,以及突然要求进行区域灾难和公共卫生规划。本文为临床医生提供有关炭疽诊断和管理的临床相关信息。