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Comparison of the experience with acute and chronic electrically stimulated detrusor myoplasty.

作者信息

Van Savage John G, Perez-Abadia Gustavo, Palanca Lucio G, Bardoel Janou W, Harralson Thomas, Amin Mohammad, Palacio Martin, Tobin Gordon, Maldonado Claudio, Barker John H

机构信息

Division of Urology, Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA.

出版信息

Neurourol Urodyn. 2002;21(5):516-21. doi: 10.1002/nau.10035.

Abstract

AIMS

To evaluate the acute and chronic urodynamic effects of electrically stimulated detrusor myoplasty in dogs.

METHODS

Eight female mongrel dogs were studied acutely and six dogs chronically (0 to 12 weeks postoperatively). Bladders were wrapped with the rectus abdominis muscle, keeping an intact blood supply and at least two intercostal nerves of the flap preserved. Bladders were electrically stimulated with bipolar electrodes inserted into the muscle. Urodynamics and post void residual were measured post operatively in the acute studies and every 2 weeks for 3 months in chronic studies.

RESULTS

Acutely, the increase in intravesical pressure was 45+/-7 cm H(2)O, which resulted in a postvoid residual of 26+/-3%. In the chronic study, increases of intravesical pressure sufficient to empty the bladder during myoplasty electrical stimulation were not sustained, although detrusor compliance and flap viability were preserved.

CONCLUSIONS

The electrically stimulated detrusor myoplasty worked well acutely to increase vesical pressure sufficient to empty the bladder, but the chronically stimulated myoplasty did not maintain efficient bladder emptying primarily due to electrode problems. Further studies with improved electrode material and placement are required before clinical application of the electrically stimulated detrusor myoplasty can be assessed.

摘要

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